Archive for the ‘Gastroenterology’ Category
A proton pump inhibitor used for the treatment of reflux oesophagitis, gastric and duodenal ulcers (including those associated with Helicobacter pylori infection and the use of NSAIDs), Zollinger-Ellison syndrome, and other kinds of acid-peptic disease. It is available as capsules or a suspension on prescription only.
Side effects: include headache, dizziness, fatigue, malaise, diarrhoea, constipation, sore throat, rashes, and muscle aches.
Interactions with other drugs:
Antifungal drugs: the absorption of ketoconazole and itraconazole may be reduced by lansoprazole. Oral contraceptives: their metabolism may be accelerated (and therefore their effects reduced) by lansoprazole. Phenytoin: lansoprazole should be used with caution in people taking phenytoin.
Warfarin: lansoprazole should be used with caution in people taking warfarin.
Proprietary preparation: Zoton.
An H2-receptor antagonist used in the treatment of duodenal or gastric ulcers, ulcers caused by use of NSAIDs, and gastro-oesophageal reflux disease, and for the prevention of ulcer recurrence.
It is available as capsules or an injection on prescription only. Packs containing no more than two weeks’ supply of capsules, for the treatment and prevention of indigestion and heartburn in those over 16 years old, can be obtained from pharmacies without a prescription.
Side effects: include anaemia, sweating, itching, hepatitis, and jaundice.
Precautions: nizatidine should be used with caution by people with liver or kidney disease and by women who are pregnant or breastfeeding.
Proprietary preparations: Axid; Zinga.
