Archive for the ‘Arthritis’ Category
Used for the treatment of ankylosing spondylitis (a type of arthritis affecting the spine) when this has not
responded to other drugs. It is used only under supervision in hospital because it occasionally causes severe side effects. Phenylbutazone is available as tablets on prescription only.
Side effects of phenylbutazone may include inflammation of the lining of the mouth and salivary glands,
enlargement of the thyroid gland (goitre), hepatitis, and blood disorders.
Anyone taking phenylbutazone who develops a sore throat, mouth ulcers, bruising, fever, malaise, or a rash should inform a doctor immediately.
Interactions with other drugs:
Phenytoin: its effects are enhanced by phenylbutazone.
Warfarin: should not be taken with phenylbutazone, as phenylbutazone greatly increases its anticoagulant effects.
Proprietary preparation: Butacote.
An NSAID used for the treatment of pain and mild inflammation in rheumatoid arthritis and other disorders of muscles or joints.
It is also used to relieve period pains, acute gout, sciatica, and pain occurring after orthopaedic surgery. It is available, on prescription only, as capsules, modified-release capsules, suppositories, an injection, and a gel for topical application (some gel formulations are also available without a prescription).
Suppositories may cause local irritation: there may be pain at the site of the injection.
Proprietary preparations: Boots Muscular Pain Relief Gel; Fenoket (modified-release capsules); Jomethid XL (modified-release capsules); Ketil CR (modified-release capsules); Ketocid (modified-release capsules); Ketoprofen CR (modified-release capsules); Ketotard 200 XL (modified-release capsules); Ketovail (modified-release capsules); Ketozip XL (modified-release capsules); Larafen CR (modified-release capsules); Orudis (capsules and suppositories); Oruvail (modified-release capsules, gel, and injection);
Powergel (gel); Solpaflex Gel.
