A proton pump inhibitor used for the treatment of reflux oesophagitis, gastric and duodenal ulcers (including those associated with Helicobacter pylori infection and the use of NSAIDs), Zollinger-Ellison syndrome, and other kinds of acid-peptic disease. It is available as capsules or a suspension on prescription only.
Side effects: include headache, dizziness, fatigue, malaise, diarrhoea, constipation, sore throat, rashes, and muscle aches.
Interactions with other drugs:
Antifungal drugs: the absorption of ketoconazole and itraconazole may be reduced by lansoprazole. Oral contraceptives: their metabolism may be accelerated (and therefore their effects reduced) by lansoprazole. Phenytoin: lansoprazole should be used with caution in people taking phenytoin.
Warfarin: lansoprazole should be used with caution in people taking warfarin.
Proprietary preparation: Zoton.
