An antidepressant drug of the SSRI group. It is used for the treatment of depressive illness, obsessive-compulsive disorder, and bulimia nervosa. Fluoxetine is available as capsules or liquid on prescription only.
Interactions with other drugs:
Antiepileptics: the plasma concentrations of carbamazepine and phenytoin are increased by fluoxetine.
Antipsychotics: plasma concentrations of clozapine, haloperidol, and sertindole are increased by fluoxetine. Selegiline: there is an increased risk of hypertension and adverse effects on the central nervous system.
Terfenadine: there is an increased risk of arrhythmias and fluoxetine should not be taken with terfenadine.
Proprietary preparation: Prozac.
