Health Blog

Used for the treatment of ankylosing spondylitis (a type of arthritis affecting the spine) when this has not
responded to other drugs. It is used only under supervision in hospital because it occasionally causes severe side effects. Phenylbutazone is available as tablets on prescription only.
Side effects of phenylbutazone may include inflammation of the lining of the mouth and salivary glands,
enlargement of the thyroid gland (goitre), hepatitis, and blood disorders.
Anyone taking phenylbutazone who develops a sore throat, mouth ulcers, bruising, fever, malaise, or a rash should inform a doctor immediately.
Interactions with other drugs:
Phenytoin: its effects are enhanced by phenylbutazone.
Warfarin: should not be taken with phenylbutazone, as phenylbutazone greatly increases its anticoagulant effects.
Proprietary preparation: Butacote.

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